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Wednesday, September 11, 2019

Statins Shown to Extend Life by Mere Days

A 2018 review presents substantial evidence that total cholesterol and LDL cholesterol levels are not an indication of heart disease risk, and that statin treatment is of “doubtful benefit” as a form of primary
prevention for this reason.
Tactics used in statin studies to exaggerate benefits include excluding unsuccessful trials, cherry-picking data, ignoring the most important outcome — an increase in life expectancy — and using a statistical
tool called relative risk reduction to amplify trivial effects
If you look at absolute risk, statin drugs benefit just 1% of the treated participants. Out of 100 people treated with statins for five years, one person will have one less heart attack
Statin trials minimize health risks by using a run-in period. Participants are given the drug for a few weeks, after which those who suffer adverse effects are simply excluded, thereby lowering the perceived
frequency and severity of side effects
https://articles.mercola.com/sites/articles/archive/2019/09/11/do-statins-prolong-life.aspx?utm_source=dnl&utm_medium=email&utm_content=art1HL&utm_campaign=20190911Z1&et_cid=DM341182&et_rid=705731296

Tuesday, September 3, 2019

Research confirms fluoride lowers children's IQ

  • A U.S. and Canadian government-funded observational study found that drinking fluoridated water during pregnancy lowers children’s IQ
  • A 1 milligram per liter increase in concentration of fluoride in mothers’ urine was associated with a 4.49-point decrease in IQ among boys only, while a 1-mg higher daily intake of fluoride was associated with a 3.66 lower IQ score in both genders between ages 3 and 4
  • The findings were hotly criticized by pro-fluoride agents, including the American Council on Science and Health (ACSH) and the Science Media Centre (SMC), two well-known front groups for the chemical industry
  • There are at least 60 other studies showing fluoride exposure damages children’s brains and lowers IQ. There are also more than 2,000 other studies detailing other health effects
  • Research published in 2017 found that, compared to a mother who drinks fluoride-free water, a child of a mother who drinks water with 1 part per million of fluoride can be predicted to have an IQ that is 5 to 6 points lower. They also found there was no threshold below which fluoride did not affect IQ.  Article from Dr. Mercola

The August 19, 2019, issue of JAMA Pediatrics1 delivered an unexpected bombshell: A U.S. and Canadian government-funded observational study found that drinking fluoridated water during pregnancy lowers children's IQ.
The research, led by a Canadian team of researchers at York University in Ontario, looked at 512 mother-child pairs living in six Canadian cities. Fluoride levels were measured through urine samples collected during pregnancy.
They also estimated the women's fluoride consumption based on the level of fluoride in the local water supply and how much water and tea each woman drank. The children's IQ scores were then assessed between the ages of 3 and 4. As reported by the Fluoride Action Network (FAN):2
"They found that a 1 mg per liter increase in concentration of fluoride in mothers' urine was associated with a 4.5-point decrease in IQ among boys, though not girls.
When the researchers measured fluoride exposure by examining the women's fluid intake, they found lower IQ's in both boys and girls: A 1 mg increase per day was associated with a 3.7 point IQ deficit in both genders."

Support for the importance of this study

The findings were deemed so controversial, the study had to undergo additional peer-review and scrutiny before publication, making it one of the more important fluoride studies to date.
Its import is also demonstrated by the fact that it's accompanied by an editor's note3 explaining the journal's decision to publish the study, and a podcast4 featuring the chief editors of JAMA Pediatrics and JAMA Network Open, in which they discuss the study.
An additional editorial5 by David Bellinger, Ph.D., a world-renowned neurotoxicity expert, also points out that "The hypothesis that fluoride is a neurodevelopmental toxicant must now be given serious consideration." Few studies ever receive all of this added treatment. According to the editor's note:6
"Publishing it serves as a testament to the fact that JAMA Pediatrics is committed to disseminating the best science based entirely on the rigor of the methods and the soundness of the hypotheses tested, regardless of how contentious the results may be."

Chemical industry front groups defend fluoride safety

Surprisingly, the findings were widely reported by most major media outlets, including Reuters,7 The Washington Post,8 CNN, NPR, Daily Beast and others, effectively reigniting the scientific debate about whether water fluoridation is a good idea.
Not surprisingly, the findings were hotly criticized by pro-fluoride agents, including the American Dental Association (ADA),9 the American Council on Science and Health10 (ACSH) and the Science Media Centre11 (SMC).
It's well worth noting that the ACSH and SMC are well-known front groups for the chemical industry, and they will defend all chemicals, regardless of what's under discussion, so seeing dismissive articles from these groups is more or less par for the course. You can learn more about these groups in the articles hyperlinked above.
It's also worth noting that Fox, which in 2014 made a similar study headline news,12 wasn't satisfied with just presenting the latest study as news and, instead, invited its resident doctor, Marc Siegel, to comment13 — and that comment began by blaming tooth decay, not fluoride, on lower IQs. Siegel ended with a rambling diatribe against the study and a scathing criticism of JAMA Pediatrics for even having published it:
"I'm far more worried about tooth decay than I am about fluoride … There's no way that fluoride would lower your IQ more than having tooth decay … It's a ridiculous study … complete poppycock … The Journal of the American Medical Association Pediatrics should not have put this in."
As for the ADA, it's been promoting water fluoridation as a health benefit for over a century and a half. To change its stance would clearly result in a loss of face, and might even expose the association to liability. The loss of scientific credibility alone is likely enough to encourage the ADA to hold on to the status quo.
The same goes for the U.S. Centers for Disease Control and Prevention which, despite the more than 2,700 studies14 against it, maintains water fluoridation is one of the top 10 great public health achievements of the 20th century.15

AAP support of water fluoridation is hypocritical

A bit tougher to explain is the American Academy of Pediatrics' support of water fluoridation.16 Of any group, the AAP really should reconsider its stance on this issue, seeing how it has officially recognized the hazardous influence of hormone-disrupting chemicals on child development.
In 2018, the AAP issued a policy statement17 warning parents to avoid endocrine disrupting chemicals — commonly found in processed foodfast food wrappers and plastics, for example — and while fluoride was not specified as an example of a chemical to be avoided, research shows fluoride has hormone disrupting potential, placing it in the exact same category. As noted by FAN:18
"Fluoride was definitively identified as an endocrine disruptor in a 2006 report19,20 by the U.S. National Research Council of the National Academies (NRC). This report states:
'In summary, evidence of several types indicates that fluoride affects normal endocrine function or response ... Fluoride is therefore an endocrine disruptor in the broad sense of altering normal endocrine function or response … The mechanisms of action … appear to include both direct and indirect mechanisms …"

Fluoride Action Network addresses study critique

In the featured video, Paul Connett, Ph.D., founder and current director of the FAN, addresses some of the criticism and why this particular study is such an important wake-up call for health care practitioners and pregnant women.
"[Fluoride exposure] during pregnancy will lower the IQ of their children. Only if you think a child's tooth is more important than a child's brain would you not be disturbed by that,"Connett says. "You can repair a child's tooth. You cannot repair a child's brain once it's been impacted during fetal development."
One pro-fluoride critique against the JAMA Pediatric study is that it doesn't show cause and effect. "Well, no epidemiological study proves cause and effect," Connett says. "That's a given! To say it doesn't show cause and effect is a redundant statement." Other pro-fluoride voices argue the effect size is small — only 4.49 IQ points21 for boys, on average. However, as Connett points out:
"If you shift the entire population over by 3 or 4 IQ points, you would almost halve the number of geniuses in your society … and you would increase by about 50% the number of mentally handicapped children. So, on a population [basis] such shifts are highly, highly significant."
A third manufactured controversy revolves around the fact that only boys were impacted by maternal urine levels of fluoride. Some hitch their critique of the study on this simple gender difference.
However, it should come as no surprise that boys and girls can be affected in different ways by the same toxic compound, as their development is affected by various hormones, including sex hormones, and toxins affect various hormones in different ways. We've seen this type of gender difference in many other instances as well.
"However you cut it, you have to be so wedded to fluoridation not to take this incredibly seriously," Connett says. "Remember, there is absolutely no evidence whatsoever — no scientific evidence — that a fetus exposed to fluoride has lowered dental decay.
There's no evidence you're protecting the baby from future decay during pregnancy. So, ANY evidence suggesting it may be damaging the brain has to be taken seriously …
We have potential harm [on the one side] … and on the other side you have something that is totally unnecessary. Why on earth would any doctor hesitate to advise pregnant women: 'Don't drink fluoridated water during pregnancy'?"

Other studies support link between fluoride and IQ loss

What's more, as Connett so strongly points out, while this particular study has received a great deal of media attention, it's not the only one raising a red flag. There are at least 60 other studies listed in FAN's scientific database22 showing that fluoride exposure damages children's brains and lowers IQ.
There are also a couple of thousand other studies detailing other adverse health effects. When you add in animal research, there are more than 300 studies demonstrating fluoride can cause:23
  • Brain damage, especially when coupled with iodine deficiency
  • Reduced IQ
  • Impaired ability to learn and remember
  • Neurobehavioral deficits such as impaired visual-spatial organization
  • Impaired fetal brain development
In his video commentary, Connett briefly mentions the importance of the 2017 "Bashash study." This was an international study effort led by professor Howard Hu, who at the time of the study's publication was at the University of Toronto. The study is known as the "Bashash study" after the lead author, Morteza Bashash, Ph.D. The team also includes researchers from McGill, Harvard, Mount Sinai, Michigan, Indiana and the National Institute of Public Health of Mexico.
Funding for this research came from the U.S. National Institutes of Health, National Institute of Environmental Health Sciences and the U.S. Environmental Protection Agency. The finalized study24,25was published in the September 2017 issue of Environmental Health Perspectives.
This study was remarkable for the fact that it followed participants for 12 years, involved several well-respected researchers, employed rigorous methodology and controlled for virtually all conceivable factors.
Here too, they found a strong relationship between the urinary level of fluoride in pregnant women and the subsequent IQ in their children. They also found a dose-dependent relationship, so the higher the mother's urine level of fluoride, the lower the IQ in the offspring.
According to the Bashash study, compared to a mother who drinks fluoride-free water, a child of a mother who drinks water with 1 part per million of fluoride can be predicted to have an IQ that is 5 to 6 points lower. What's more, they found there was no threshold below which fluoride did not affect IQ.

Your contributions are making a difference

FAN is part of the Mercola Health Liberty Coalition, founded in 2011 — the mission of which is to inform and educate about the fraud and deceptions created by the junk food, chemical and pharmaceutical industries. Other Health Liberty partners include the National Vaccine Information Center, the Organic Consumers Association and Consumers for Dental Choice.
Not only has your support been helpful to catalyze the removal of fluoride but you have been able to help us make massive changes with two other health issues as well:
  • GMOs — When we first started, the average person in the U.S. did not know what GMOS were. Now, not only do they know but they are also aware how dangerous they are. Your support has allowed FOIA requests to be filed that produced critical evidence resulting in juries awarding plaintiffs billions of dollars from Bayer/Monsanto, with another 13,000 cases pending and a possibility of bankrupting this evil giant.
  • Dental mercury — Charlie Brown has coordinated worldwide bans on the use of mercury in dentistry that has already resulted in banning mercury in dentistry in many countries, with the likely complete elimination of amalgam within the next few years.
Again and again, we see "controversial" and "contentious" stances proven prudent and correct given enough time for sufficient science to accumulate. It's important for you to recognize that your donations to these organizations through the years have allowed these successes to manifest. The latest JAMA Pediatrics study brings us another major step forward in the process to eliminate water fluoridation.

Editors compare anti-fluoridation to anti-vaccine sentiments

As noted by JAMA Pediatrics editor-in-chief, Dr. Dimitri Christakis, in the JAMA podcast (embedded above):
"Before there were anti-vaxxers there were anti-fluoriders, and the traditional teaching when I was going through residency in my early professional career was, 'fluoride is completely safe and all of these people trying to take it out of the water are nuts. It's the best thing that's ever happened for children's dental health and we need to push back and get it into every water system' …
So, when I first saw this title ['Association Between Maternal Fluoride Exposure During Fetal Development and IQ Scores in Offspring in Canada'], my initial inclination was, 'What the hell?"
Christakis goes on to express shock at the discovery that only 3% of European residents, while 66% of Americans and 38% of Canadians drink fluoridated water (statistics noted in the JAMA Pediatrics paper26), as he was under the assumption that all developed countries fluoridated all their water supplies. This just goes to show the general ignorance that still exists even among well-educated health professionals.
Christakis and JAMA Network Open editor-in-chief Dr. Frederick Rivara also express mutual surprise that the effect of water fluoridation on IQ was so great. They point out that a 5-point reduction is significant indeed, as it's "on par with lead."
Christakis goes on to discuss the fact that there have been other studies suggesting fluoride may be a neurotoxin. "Which, again, was totally news to me. I thought it was junk science," he says. Rivara agrees, saying such studies have in the past been likened to "junk" anti-vaccine science.
Christakis admits he struggled with the findings — basically because of his preconceptions of the science. He certainly did not want to be the one putting out "junk science" that might lead to a deterioration of children's dental health. This is precisely why the study was put through additional reviews to make sure the methodology and findings were sound. In the end, the research was solid enough to pass the tests.
It's interesting to hear Christakis and Rivara talk about their struggle to accept the idea that water fluoridation may be harmful — at the very least until the child starts developing teeth. But even toddlers may be harmed, the pair admit, as toddlers and young children's brains are still developing.
It's even more interesting to hear them equate their struggles to that of the vaccine safety question for, indeed, the very same struggle to accept the idea that vaccines can cause harm is identical to the struggle to accept that water fluoridation may be damaging our children.
Both are considered unassailable public health victories, and no one wants to entertain the idea that we may inadvertently be causing grave harm on a populationwide basis. Yet that's a very real probability, as this study shows (and many others as well).

Fluoride is an environmental pollutant as well

Overall, it makes absolutely no sense to fluoridate municipal water supplies. First of all, it's forced medication without oversight — there's no way to ascertain the dosage any given person is getting, or what effect it's having on their health.
When it comes to fetuses and infants, water fluoridation is useless, as there's no scientific evidence to even remotely suggest it has a beneficial impact on future dental health, and it certainly does not make sense to "prevent cavities" in those without teeth.
Furthermore, the vast majority of the fluoride in the water never ever touches a tooth. It's simply flushed down the drain, becoming an environmental pollutant. As noted by Edward Groth III, a staff officer on the Environmental Studies Board, Commission on Natural Resources, with the National Research Council back in 1975:27
"Environmental contamination by fluorides exposes many organisms to potentially toxic effects and may exert some stress on the ecological interrelationships among plant and animal populations … [T]he available evidence does support the view that fluorides are pollutants with considerable potential for producing ecological damage."
Groth's article, "Fluoride Pollution,"28 which appeared in the journal Environment: Science and Policy for Sustainable Development, summarizes the ecological impacts of low-level fluoride pollution, pointing out fluoride has been found to accumulate in the bodies of insects, birds and mammals, in some cases to potentially toxic levels, thus increasing fluoride levels in the food chain as a whole.
There are also reports of toxic effects in algae and freshwater vertebrates, and "indications that aquatic vegetation may also concentrate the element." Substantial amounts of fluoride are also entering farmland, where it's taken up by soil organisms.
"Possible conversion of fluoride into fluoracetate (more toxic than fluoride itself and related organic forms), and the likelihood that fluoride may enter into synergistic actions with other contaminants, greatly expand the potential for ecological damage by low-level fluoride contamination," Groth writes.29

Water fluoridation is a clear form of water contamination

It's also important to realize that the fluoride added to our water is an untreated industrial waste product from the fertilizer industry — not a pharmaceutical grade product — that is suddenly deemed a health product once it's purposely added to water.
As long as the chemical is on the premises of a fertilizer company, it's actually classified as hazardous waste, requiring costly disposal measures to comply with hazardous waste regulations.
This fluorosilicic acid is frequently contaminated with lead, arsenic, uranium, radium, aluminum and other industrial contaminants. In other words, water fluoridation can be likened to a legal water contamination scheme.
For a review of the oft-neglected history of water fluoridation, read through "Toxic Treatment: Fluoride's Transformation from Industrial Waste to Public Health Miracle" in the March 2018 issue of Origins,30 a joint publication by the history departments at The Ohio State University and Miami University. As noted in "Toxic Treatment:"
"Without the phosphate industry's effluent, water fluoridation would be prohibitively expensive. And without fluoridation, the phosphate industry would be stuck with an expensive waste disposal problem."
There's also very little evidence to suggest water fluoridation actually has a beneficial impact on tooth decay, while there's unequivocal evidence of harm, as it causes dental fluorosis. Origins writes:31
"Only a handful of countries fluoridate their water — such as Australia, Ireland, Singapore, and Brazil, in addition to the United States. Western European nations have largely rejected the practice. Nonetheless, dental decay in Western Europe has declined at the same rate as in the United States over the past half century …
This is not to vilify the early fluoridationists, who had legitimate reason to believe that they had found an easy and affordable way to counter a significant public health problem.
However, the arguments and data used to justify fluoridation in the mid-20th century — as well as the fierce commitment to the practice — remain largely unchanged, failing to take into account a shifting environmental context that may well have rendered it unnecessary or worse."

Monday, August 19, 2019

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Tuesday, August 6, 2019

Added Sugars Negatively Impact Immune System - Most Americans exceed recommendations for sugar intake

by Whitney Crouch, RDN, CLT

Sugar is a hot topic. It’s one of the recently recognized, major culprits for increasing rates of overweight and obesity, type 2 diabetes, and heart disease and contributes to a multitude of other health conditions related to inflammation in the body.1

Sugar intake in America
42% of Americans at 2 years meet the 2015-2020 Dietary Guidelines for Americans recommendation for limiting added sugars intake to 10% of daily calories from added sugars, and the actual amount of sugar consumed by these individuals is staggering.

On average, those who met the Dietary Guidelines recommendation consumed almost 7 teaspoons of added sugars daily, and those who did not consumed about 25 teaspoons of added sugars/day (1 tsp of added sugar = 4.2 grams of sugar),1 which is about 420 calories/day from added sugars alone.

Examples of added sugars include brown sugar, corn sweetener, corn syrup, dextrose, fructose, glucose, high-fructose corn syrup, honey, lactose, malt syrup, maltose, molasses, raw sugar, and sucrose.2

Excessive sugar intake: long-term consequences
Sugar is thought to be a pro-inflammatory agent in the body. When blood sugar levels are elevated for extended periods of time, the body may be placed into an inflammatory state, which can lead to cellular dysfunction and changes to both the innate and adaptive immune systems. It is postulated that elevated sugar intake produces elevated free fatty acid production by the liver, which may trigger the inflammatory process and increase reactive oxidative species (ROS) formation.3

The innate immune system represents the dominant defense system against most organisms; it has a fast response to infection but no immunological memory.4 In contrast, the adaptive immune system has immunological memory that promotes quick elimination of pathogens when reinfection with the same pathogen occurs. It includes T and B lymphocytes and antibodies.5

Obesity, physical inactivity, and consumption of excess refined sugars have been associated with an increased risk of type 2 diabetes, as well as autoimmune and inflammatory diseases.6,7 Obese individuals have fewer white blood cells to fight infections, and the cells they do possess have reduced phagocytic capability.8 Sustained hyperglycemia, such as in diabetes, is associated with an elevated risk of autoimmune and inflammatory diseases (i.e., rheumatoid arthritis, asthma, psoriasis), as well as cancer.9

Excessive sugar intake: short-term consequences
The link between excess body weight, type 2 diabetes, tooth decay, and heart disease from overconsumption of sugar are well established.5 But what does too much sugar do to the fast-acting, innate immune system? Studies have looked at what happens in the blood after consumption of large amounts of sugar, and in short, depressing effects on the innate immune system were seen.10,12

One such study looked at the blood after healthy study participants consumed 100 g (25 teaspoons) of sucrose, glucose, or fructose.10 As a result of the high sugar intake (which also happens to be the average intake of added sugars in 58% of Americans), there was a transient 50% decrease in neutrophils’ capacity to engulf bacteria in the 1-2 hours after the sugary drink was consumed.10 Neutrophils are the most common type of white blood cell (WBC), comprising 55-70% of the WBC count, and are responsible for immediate responses to infection or attacks on the body’s cells.11

Another study looked at the phagocytic capacity of neutrophils in healthy students who either ingested a sugar-containing or sugar-free beverage. No neutrophil abnormalities were found after drinking the sugar-free drink, however there was a significant decrease in the mean phagocytic (ability to engulf pathogens) index after in the group ingesting the sugar-containing drink.12

Together, these studies shine light on the body’s impaired ability to fight off bacterial invaders when high sugar drinks are consumed – a trend that is prevalent in the Standard American Diets.1

The leading sources of added sugars in the US diet are sugar-sweetened beverages, grain-based desserts like cakes and cookies, candy, and dairy desserts such as ice cream.13 For reference, one 16-oz bottle of Coca-Cola contains 52 g of added sugar (or ~13 tsp of added sugar).14

Sugar intake and your health
Added sugars are ubiquitous in processed foods. To limit intake of sugar to achieve the recommended 1

In addition to dietary awareness, maintaining regular exercise helps support healthy blood glucose levels. Exercise is the most potent physiological inducer of efficient glucose storage and reduces the severity of hyperglycemic events, in addition to the risk and severity of autoimmune diseases.9 Muscular uptake of blood glucose helps to regulate circulating blood post-prandial blood sugars, and the greater the muscle mass, the greater the uptake of blood sugars.15

Healthcare providers would be wise to assess intake of added sugars in the diet of their patients and partner to provide recommendations and implementation tools for their patients to achieve healthful, nutrient-dense dietary patterns that suit their personal health needs and preferences.

Citations
  1. Bowman SA et al. Added sugars intake of Americans: What we eat in America, NHANES 2013-2014. Food Surveys Research Group. Dietary Data Brief No. 18. May 2017.
  2. USDHHS and USDA. Added sugars. 2015–2020 Dietary Guidelines for Americans. http://health.gov/dietaryguidelines/2015/. Accessed November 29, 2018.
  3. Della Corte KW et al. Effect of dietary sugar intake on biomarkers of subclinical inflammation: a systematic review and meta-analysis of intervention studies. Nutrients. 2018;10(5):606.
  4. Inweregbu K et al. Nosocomial infections. Contin Educ Anaesth Crit Care Pain. 2005;5(1):14–17.
  5. Janeway CA Jr et al. Immunobiology: The Immune System in Health and Disease: Principles of Innate and Adaptive Immunity. 5th ed. New York:2001.
  6. Malik VS et al. Sugar-sweetened beverages, obesity, type 2 diabetes mellitus, and cardiovascular disease risk. Circulation. 2010;121(11):1356-1364.
  7. Gaby A. A review of the fundamentals of diet. Glob Adv Health Med. 2013;2(1):58-63.
  8. Nieman DC et al. Influence of obesity on immune function. J Am Diet Assoc. 1999;99(3):294–299.
  9. Hansen NW et al. The endothelial border to health: Mechanistic evidence of the hyperglycemic culprit of inflammatory disease acceleration. IUBMB Life. 2017;69(3)L148–L161.
  10. Sanchez A et al. Role of sugars in human neutrophilic phagocytosis. Am J Clin Nutr. 1973;26:1180–1184.
  11. American Society of Hematology. Blood Basics. http://www.hematology.org/Patients/Basics/. Accessed November 16, 2018.
  12. Ringsdorf WM Jr et al. Sucrose, neutrophilic phagocytosis and resistance to disease. Dental Survey.1976;52:46-48.
  13. Drewnowski A et al. Consumption of added sugars among US children and adults by food purchase location and food source. Am J Clin Nutr. 2014;100(3):901-907.
  14. Coca-colaproductfacts.com. How Much Sugar In Coke Is There? | Product Facts. https://www.coca-colaproductfacts.com/en/faq/sugar/how-much-sugar-in-coke/. Accessed November 16, 2018.
  15. Sylow L et al. Exercise-stimulated glucose uptake – regulation and implications for glycaemic control. Nat Rev Endocrinol. 2017;13(3):133-148. 
Whitney Crouch, RDN, CLT 
Whitney Crouch is a Registered Dietitian who received her undergraduate degree in Clinical Nutrition from the University of California, Davis. She has over 10 years of experience across multiple areas of dietetics, specializing in integrative and functional nutrition and food sensitivities. When she’s not writing about nutrition or educating others, she’s spending time with her husband and young son. She’s often found running around the bay near her home with the family’s dog or in the kitchen cooking up new ideas to help her picky eater expand his palate.

How do kids end up with higher levels of weed killer?